Controlling Amphiphilic Functional Block Copolymers’ Self-Assembly: From Structure to Size
نویسندگان
چکیده
Nanostructure of self-assembled particles, such as micelles and polymersomes play an important role in drug delivery, especially in tumor therapy. Particles with various structures are regarded as perfect candidates for controlled drug delivery due to highly selective cellular uptake and exceptional payload that increases drug delivery efficiency [1-4]. Size, as another benefit that can be controlled precisely from self-assembly provided the possibilities of positive targeting. Controllable size (20 ~ 500 nm) benefits the extended permeation and retention (EPR) and enhances the tumor therapy as reported by several studies [5-8].
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